NOS1‐dependent S‐nitrosylation of cardiac calcium‐handling proteins (RyR2, SERCA, and L‐type Ca2+ channel) modulates basal contractility and adrenergic inotropism

Autor:	Daniel R. Gonzalez, Gisela Eller, Mauricio P. Boric, Alejandra Z. Vielma
Rok vydání:	2012
Předmět:	medicine.medical_specialty SERCA Chemistry NOS1 Adrenergic S-Nitrosylation Biochemistry Ryanodine receptor 2 Contractility Basal (phylogenetics) Endocrinology Inotropism Internal medicine Genetics medicine Molecular Biology Biotechnology
Zdroj:	The FASEB Journal. 26
ISSN:	1530-6860 0892-6638
Popis:	We tested the hypothesis that NOS-1 activity regulates basal and β-adrenergic-stimulated cardiac contractility by S-nitrosylation of Ca2+-handling proteins. We used the isolated rat heart preparati...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::883920d80e45ed8835a8dbf2f82bdc1a https://doi.org/10.1096/fasebj.26.1_supplement.1139.5 Zobrazit plný text záznamu Plný text