Therapeutic Trial of Hematological Disorders with Intermittent Administration of High-Dose 1-Alpha-Hydroxyvitamin D3

Autor:	Masaharu Tsutsumi, Yasuo Imai, Takuo Fujita, Toshimitsu Matsui, Masashi Nishikawa, Tohru Tsunenari, Toshiki Natazuka
Rok vydání:	2015
Předmět:	Hematological disorders medicine.medical_specialty business.industry Alpha (ethology) medicine.disease Therapeutic trial Gastroenterology Surgery Internal medicine medicine Hypercalciuria Aplastic anemia Adverse effect business
DOI:	10.1159/000420163
Popis:	Aplastic anemia and myelodysplastic syndrome were successfully treated with an intermittent administration of high-dose 1 alpha-hydroxy-vitamin D3, an active analogue of 1,25-dihydroxyvitamin D3. This effect was considered to be through the differentiation-inducing and immunomodulatory actions of 1,25-dihydroxyvitamin D3. The only adverse effect was hypercalciuria which was controllable by decreasing the dose.
Databáze:	OpenAIRE
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