Polymorphic variants of ALOX5AP gene and the risk of acute stroke development in the Russian population

Autor:	E. A. Bondarenko, P. A. Slominsky, Shetova Im, Skvortsova Vi, D. Yu. Timofeev, Svetlana A. Limborska
Rok vydání:	2011
Předmět:	Genetics Ischemic stroke Russian population ALOX5AP gene Single-nucleotide polymorphism cardiovascular diseases Biology Control sample Bioinformatics Gene Human genetics Acute stroke
Zdroj:	Russian Journal of Genetics. 47:500-503
ISSN:	1608-3369 1022-7954
Popis:	The role of variants of the gene encoding arachidonate 5-lipoxygenase-activating protein (ALOX5AP) as possible susceptibility factors for acute stroke were examinated. Two ALOX5AP gene polymorphisms (SG13S114 (rs10507391) and SG13S32 (rs9551963)), which previously had shown association with the risk of ischemic stroke in other populations, were studied. These single nucleotide polymorphisms were analyzed using a sample of acute stroke patients (N = 1320) and a control sample (N = 467). No statistically significant associations were found between acute stroke and the ALOX5AP gene polymorphisms examined.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::882cf32fed01116a97fd5d8741d5e3f4 https://doi.org/10.1134/s102279541104003x Zobrazit plný text záznamu Full text from SpringerLink