Pulsatility does not change cerebral oxygenation during cardiopulmonary bypass

Autor: G. Grubhofer, Angela Rajek, M. Dworschak, M. Haisjackl, T. Müllner, P. Mares, A. Lassnigg
Rok vydání: 2000
Předmět:
Zdroj: Acta Anaesthesiologica Scandinavica. 44:586-591
ISSN: 0001-5172
Popis: Background: To determine the effect of pulsatility during cardiopulmonary bypass (CPB) on cerebral oxygenation, we measured oxyhaemoglobin (HbO2), deoxyhaemoglobin (Hb) and oxidised cytochrome aa3 (CtO2) with near-infrared spectroscopy (NIRS) in 14 patients electively scheduled for cardiac surgery. Methods: Cerebral oxygenation was measured during steady state CPB at a core temperature of 32°C. Non-pulsatile flow and pulsatile flow were performed for 10 min each. Results: After 14 min of CPB, HbO2, Hb and CtO2 were significantly below prebypass values. HbO2 and CtO2 did not alter with changing flow patterns. Hb significantly increased both during the period of nonpulsatile (median: −0.7 vs. 0.25 μmol/l; P
Databáze: OpenAIRE