Pulsatility does not change cerebral oxygenation during cardiopulmonary bypass
Autor: | G. Grubhofer, Angela Rajek, M. Dworschak, M. Haisjackl, T. Müllner, P. Mares, A. Lassnigg |
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Rok vydání: | 2000 |
Předmět: |
medicine.medical_specialty
Heart disease business.industry Pulsatile flow Hemodynamics General Medicine Oxygenation Blood flow medicine.disease law.invention Cardiac surgery surgical procedures operative Anesthesiology and Pain Medicine Cerebral oxygenation law Anesthesia Cardiopulmonary bypass Medicine business |
Zdroj: | Acta Anaesthesiologica Scandinavica. 44:586-591 |
ISSN: | 0001-5172 |
Popis: | Background: To determine the effect of pulsatility during cardiopulmonary bypass (CPB) on cerebral oxygenation, we measured oxyhaemoglobin (HbO2), deoxyhaemoglobin (Hb) and oxidised cytochrome aa3 (CtO2) with near-infrared spectroscopy (NIRS) in 14 patients electively scheduled for cardiac surgery. Methods: Cerebral oxygenation was measured during steady state CPB at a core temperature of 32°C. Non-pulsatile flow and pulsatile flow were performed for 10 min each. Results: After 14 min of CPB, HbO2, Hb and CtO2 were significantly below prebypass values. HbO2 and CtO2 did not alter with changing flow patterns. Hb significantly increased both during the period of nonpulsatile (median: −0.7 vs. 0.25 μmol/l; P |
Databáze: | OpenAIRE |
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