Arrhythmia insensitive rapid cardiac T1 mapping: comparison to modified look locker inversion recovery T1 mapping in mitral valve prolapse patients

Autor: Ruth P. Lim, Ernest Cheung, Danny C. Kim, Omar Farouque, Hui-Chen Han, Andrew W. Teh, Han S. Lim, Kyung Pyo Hong, Leonid Churilov, Emma Hornsey, Julie Smith
Rok vydání: 2020
Předmět:
Zdroj: The International Journal of Cardiovascular Imaging. 36:2017-2025
ISSN: 1573-0743
1569-5794
DOI: 10.1007/s10554-020-01910-9
Popis: We compare a saturation recovery arrhythmia insensitive rapid (AIR) T1 mapping technique which is less sensitive to heart rate and requires shorter breath-holds to modified Look-Locker inversion recovery (MOLLI) T1 mapping in patients with mitral valve prolapse. 55 patients underwent AIR and MOLLI at 1.5 T. AIR and MOLLI-derived blood and myocardial T1 values and extracellular volume (ECV) were measured by two independent readers. T1 values and ECV from both techniques and inter-reader agreement were compared with Lin’s concordance correlation coefficient (LCC) and reduced major axis regression. T1 values were consistently overestimated for AIR compared to MOLLI and vice versa for ECV. In the mitral valve prolapse population, mean native and post contrast myocardial T1 value for MOLLI were 1000 ± 40 ms and 411.9 ± 44.2 ms respectively and 1090.6 ± 58.7 ms and 488.2 ± 45.7 ms for AIR. Mean native and post contrast blood T1 values for MOLLI were 1566.6 ± 72.3 ms and 276.6 ± 34.1 ms respectively versus 1657.2 ± 180.9 ms and 294.9 ± 35.6 ms for AIR. AIR underestimated ECV relative to MOLLI (23.5 ± 0.4% vs 27.7 ± 0.4%). We found excellent inter-reader agreement (LCC all > 0.94, p 0.97, p
Databáze: OpenAIRE
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