Radiographic abnormalities, bladder interventions, and bladder surgery in the first decade of life in children with spina bifida
| Autor: | Rosalia Misseri, Shelly King, Richard C. Rink, Adam J. Rensing, Martin Kaefer, Mark P. Cain, Joshua D. Roth, Konrad M. Szymanski, Katherine H. Chan, Benjamin Whittam |
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| Rok vydání: | 2019 |
| Předmět: |
Nephrology
medicine.medical_specialty Creatinine Spina bifida business.industry Incidence (epidemiology) 030232 urology & nephrology Renal function 030204 cardiovascular system & hematology medicine.disease Surgery 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine chemistry Internal medicine Pediatrics Perinatology and Child Health medicine Stage (cooking) business Hydronephrosis Kidney disease |
| Zdroj: | Pediatric Nephrology. 34:1277-1282 |
| ISSN: | 1432-198X 0931-041X |
| DOI: | 10.1007/s00467-019-04222-w |
| Popis: | Spina bifida (SB) patients are at increased risk for hydronephrosis, bladder storage and emptying problems, and renal failure that may require multiple bladder surgeries. We retrospectively reviewed patients born with SB 2005–2009, presenting to our institution within 1 year of birth. Outcomes at 8–11 years old included final renal/bladder ultrasound (RBUS) results, clean intermittent catheterization (CIC) use, anticholinergic use, surgical interventions, and final renal function. We excluded those without follow-up past age 8 and/or no RBUS or fluoroscopic urodynamic images (FUI) within the first year of life. Imaging was independently reviewed by four pediatric urologists blinded to radiologists’ interpretation and initial findings compared with final outcomes. Of 98 children, 62 met inclusion criteria (48% male, 76% shunted). Median age at last follow-up was 9.6 years. Upon initial imaging, 74% had hydronephrosis (≥ SFU grade 1), decreasing to 5% at 10 years (p |
| Databáze: | OpenAIRE |
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