Effects of substituents in acid-catalyzed Claisen amino rearrangement

Autor:	N. G. Nigmatullin, Tolstikov Genrikh A, Z. N. Saraeva, V. D. Komissarov, Abdrakhmanov Ildus B
Rok vydání:	1989
Předmět:	Nitrobenzene chemistry.chemical_compound Reaction rate constant Chemistry Stereochemistry Acid catalyzed Substrate (chemistry) Reactivity (chemistry) General Chemistry Selectivity Medicinal chemistry
Zdroj:	Bulletin of the Academy of Sciences of the USSR Division of Chemical Science. 38:2117-2122
ISSN:	1573-9171 0568-5230
DOI:	10.1007/bf00962120
Popis:	A series of 4-R2-N-R1-N-(1-methyl-2-butenyl)- and 4-R2-N-R1-2-(1-methyl-2-butenyl)-anilines was synthesized. The rate constants of rearrangement and elimination of the hydrochlorides of the 4-R2-N-R1-N-(-1methyl-2-butenyl)anilines in nitrobenzene were measured at 110 and 130°C. The correlation equations which describe the effect of the nature of the substituents on the reactivity of the substrate in these reactions and the selectivity of their occurrence were established. A mechanism of the processes was proposed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8812d6d2cc43257a2a4f03845581cdfc https://doi.org/10.1007/bf00962120 Zobrazit plný text záznamu Full text from SpringerLink