THE INFLUENCE OF COMPLEX ANTIOXIDANT THERAPY ON THE DYNAMICS OF CHANGES OF OXIDANT STRESS INDICES IN THE BODY OF PREGNANT WOMEN WITH DIFFUSE TOXIC GOITER
| Autor: | M. O. Kostiv, O.S. Payenok, A. V. Payenok, B. V. Zadorozhna |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Pregnancy Antioxidant Goiter business.industry medicine.medical_treatment Physiology General Medicine medicine.disease Lipid peroxidation 03 medical and health sciences chemistry.chemical_compound 030104 developmental biology 0302 clinical medicine chemistry Diffuse toxic goiter medicine business 030217 neurology & neurosurgery |
| Zdroj: | Clinical & experimental pathology. 18 |
| ISSN: | 1727-4338 |
| DOI: | 10.24061/1727-4338.xviii.1.68.2019.15 |
| Popis: | Objective of the article is to study the effect of antioxidant therapy on the level of lipidsperoxidation products and antioxidant defense system in pregnant women with diffusetoxic goiter.Material and methods. The subject of the study was 65 pregnant women with diffusetoxic goiter of mild degree and 64 with moderate degree of severity, receiving thecommon therapy and combining the latter with the antioxidant one. The control group consisted of 30 women with physiological course of pregnancy. The initial and finalproducts of lipid peroxidation as well as enzymes of the defense antioxidant system inthe groups, were studied, depending on the received system of treatment.Results. While using the antioxidant therapy in the complex treatment of pregnantwomen with diffuse toxic goiter, the state of lipid peroxidation is likely to be normalizedin mild forms of thyrotoxicosis and with moderate degree - the tendency to levellingsimilar indicators in the group of pregnant women with a mild degree before treatmentis observedConclusions. The use of complex antioxidantal therapy is one of the pathogeneticprinciples of correction of fetoplacental insufficiency in pregnant women with diffusetoxic goiter. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|