Hyperbaric oxygen for long-term complications of radiation cystitis
| Autor: | Martinho Almeida, Manuel Cerqueira, Frederico Carmo Reis, Tiago Correia, Carlos Ferreira, Rui Prisco, Oscar Camacho, André Cardoso |
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| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Journal of Radiotherapy in Practice. 14:18-26 |
| ISSN: | 1467-1131 1460-3969 |
| DOI: | 10.1017/s1460396914000375 |
| Popis: | IntroductionBladder complications may be seen in up to 12% of patients treated with pelvic irradiation. To report the long-term efficacy of hyperbaric oxygen therapy (HBOT) on radiation-induced cystitis.MethodsWe followed 70 patients diagnosed with radiation cystitis submitted to HBOT in our institution from 2007 to 2013. All patients answered a questionnaire documenting symptom severity pre-HBOT and at the end of the follow-up period using the Late Effects of Normal Tissues – Subjective, Objective, Management, Analytical (LENT-SOMA) scale. Our treatment protocol consisted of multiple sessions (median of 40) of 100% oxygen delivery in a multiplace hyperbaric chamber at 2·4 atm for 80 minutes.ResultsWith a median follow-up of 55·5 (4–85) months, the success rate after the follow-up period in terms of haematuria resolution or improvement was 91·4%. The mean score of each subjective variable of LENT-SOMA scale (dysuria, frequency, haematuria, incontinence) were significantly lower after the follow-up period (pp=0·14). The sum of all subjective scores of LENT-SOMA scale was also significantly lower after the follow-up period (pConclusionsOur results highlight the safety and long-term benefits of HBOT on haemorrhagic radiation cystitis and other distressful bladder symptoms. |
| Databáze: | OpenAIRE |
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