Chemical studies of the tertiary structure of transfer RNA

Autor: I.L. Batey, Daniel M. Brown
Rok vydání: 1977
Předmět:
Zdroj: Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis. 474:378-385
ISSN: 0005-2787
DOI: 10.1016/0005-2787(77)90267-2
Popis: Conditions have been determined for the efficient iodination of exposed cytosine residues in the transfer RNA species, yeast tRNAPhe, Escherichia coli tRNAMetf, and yeast tRNAVal. The relative amount of iodination at each of these bases with the thallic chloride/potassium iodide reagent is shown to be independent of iodide concentration over a wide range of concentrations. These results are shown to be consistent with those derived from the use of other cytosine-specific reagents.
Databáze: OpenAIRE