| Popis: |
Modelling of oxygen transport into tissue can be considered in two steps. The first step comprises the release from the oxygen carriers, the erythrocytes, in the streaming blood up to the capillary wall. The second step models the diffusional transport in the - stagnant -tissue, including the capillary wall. Many literature models only involve the second step. The first model by Krogh (1919) used the simplified geometry of a tissue cylinder around a centrally located capillary. Since, several extensions have been made to this model establishing the basis of calculation of pO2 in muscle tissue (Hoofd, 1992). |
