Determination of Caffeine and its Metabolites in Saliva and Urine as a Measure of CYP1A2 Metabolic Activity

Autor:	Zdeněk Glatz, Jan Juřica, Aleš Mádr, Ondřej Zendulka, Miroslav Turjap, Stanislav Brejcha
Rok vydání:	2016
Předmět:	Saliva Chromatography 010405 organic chemistry Chemistry 010401 analytical chemistry Biophysics CYP1A2 Pharmaceutical Science Urine 01 natural sciences Biochemistry 0104 chemical sciences chemistry.chemical_compound Molecular Medicine Metabolic activity Caffeine
Zdroj:	Current Pharmaceutical Analysis. 12:325-332
ISSN:	1573-4129
Popis:	Byla vyvinuta nova citliva a robustni RP-HPLC metoda pro stanoveni kofeinu, 1,7 dimethylxanthinu, 1,7-dimethylmocove kyseliny, 5-acetylamino-6-formylamino-3-methyluracilu, 5-acetylamino-6-amino-3-methyluracilu, 1-methylxanthinu a 1-methylumocove kyseliny ve slinach a moci. Metoda slouži ke stanoveni metabolicke aktivity CYP1A2.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::87b307d87c5faac0ee7e30b592cc6c4f https://doi.org/10.2174/1573412912666151119212608 Zobrazit plný text záznamu