A CMOS integrated fdNIRS and tDCS system for simultaneous brain stimulation and monitoring
| Autor: | Valencia Joyner Koomson, Yun Miao |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Materials science
Transcranial direct-current stimulation Dynamic range medicine.medical_treatment Avalanche photodiode Chip 030226 pharmacology & pharmacy 03 medical and health sciences Responsivity 0302 clinical medicine CMOS Frequency domain Brain stimulation medicine 030217 neurology & neurosurgery Biomedical engineering |
| Zdroj: | MWSCAS |
| Popis: | A CMOS integrated frequency domain near infrared spectroscopy (fdNIRS) and transcranial direct current stimulation (tDCS) is designed for simultaneous brain stimulation and monitoring. The combination of optical sensing and electrical stimulation solves the incompatibility between EEG and tDCS in both time and spatial domains. A real-time closed-loop brain stimulation can be realized for neurological disorders treatment and cognitive performance enhancement. The dual-channel fdNIRS achieved a sub nW sensitivity when working with an APD with 40A/W responsivity and 1.77mm2 active area. Each fdNIRS channel provides 33dB dynamic range and up to 0.2° phase resolution with a power consumption of 30mW. Measurements on 2 milk and ink based liquid tissue phantoms successfully captured both the baseline information and dynamic change of absorption and reduced scattering coefficient. The on-chip 5-bit current stimulator can support a stimulating current between 0.6mA and 2.2mA with 1% accuracy, which meets the requirements of tDCS. The chip is fabricated in a standard 130nm CMOS process and occupies an area of 2.25mm2. |
| Databáze: | OpenAIRE |
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