| Popis: |
Prof O’Mahony began by discussing how the human gut is colonised by a wide diversity of microbes. He went on to review the evidence for how they exhibit highly evolved synergistic relationships to provide essential biological functions to the host and how the gut microbiome is influenced by many factors in early life. Prof Renz proceeded to describe the importance of establishing a stable gut microbial community, which closely tracks host growth and immune development. The mechanisms whereby delays or alterations in the establishment of these communities can lead to microbiome immaturity, raise the risk of allergy development including cow’s milk protein allergy (CMPA). Dr Forbes-Blom introduced the multiplicity of human milk oligosaccharides (HMO) and explained their position as multifunctional components that shape the developing gut microbiome and influence the developing immune system. Finally, Prof Nowak-Wegrzyn reviewed the latest trial data on supplementing specialty formulas for the management of CMPA with different HMO and reported the results. |
