The Role of 18F-FDG PET/CT in Suspected Intraocular Sarcoidosis and Tuberculosis

Autor:	Derrick P. Smit, C Burger, A Ellmann, Jennifer L Holness, Coenraad F.N. Koegelenberg, Stephanie Griffith-Richards
Rok vydání:	2019
Předmět:	PET-CT Tuberculosis business.industry Radiography medicine.disease Fluorodeoxyglucose positron emission tomography Ophthalmology Positive predicative value medicine Immunology and Allergy In patient Fdg pet ct Sarcoidosis business Nuclear medicine
Zdroj:	Ocular Immunology and Inflammation. 29:530-536
ISSN:	1744-5078 0927-3948
Popis:	Purpose: To determine the utility of fluorine-18 fluorodeoxyglucose Positron Emission Tomography Computed Tomography (FDG PET/CT) in patients with suspected ocular sarcoidosis (OS) or intraocular tuberculosis (IOTB) in a resource-constrained, TB endemic area.Methods: Independent review of the FDG PET/CTs, Computed Tomography (CT) scans and chest radiographs (CXRs) of patients with suspected OS or IOTB and inconclusive conventional workup.Results: Twenty-nine PET/CTs and CXRs were reviewed, with 38% of PET/CTs and CTs demonstrating evidence of TB or sarcoidosis, compared to 21% of CXRs. The sensitivity, specificity, positive and negative predictive values for PET/CT and CT were similar - 85.7%, 95.5%, 85.7% and 95.5% for OS, and 33.3%, 100%, 100% and 68% for IOTB respectively and for CXR, 57.1%, 100%, 100% and 88% for OS, and 16.7%, 100%, 100% and 63% for IOTB.Conclusion: PET/CT added no significant additional benefit over Chest CT in patients with suspected OS or IOTB.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::87a2db7bafb25d730e5a1da236625109 https://doi.org/10.1080/09273948.2019.1685109 Zobrazit plný text záznamu