P1741 Echocardiographic assessment of rate versus rhythm control strategy in patients with persistent atrial fibrillation
| Autor: | Radoslaw Piatkowski, Janusz Kochanowski, Marcin Szulc, Dariusz A. Kosior |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Brachial Plexus Neuritis
medicine.medical_specialty Randomization business.industry Diastole General Medicine Muscle hypertrophy Rhythm Internal medicine Persistent atrial fibrillation medicine Cardiology Radiology Nuclear Medicine and imaging Sinus rhythm Cardiology and Cardiovascular Medicine business Anti-Arrhythmia Agents |
| Zdroj: | European Heart Journal - Cardiovascular Imaging. 21 |
| ISSN: | 2047-2412 2047-2404 |
| Popis: | BACKGROUND Patients with persistent atrial fibrillation (AF) can be managed with either rhythm or rate control strategy. The restoration and maintenance of the sinus rhythm (SR) is not superior to the rate control regarding the total mortality and the rate of thromboembolic complications. Data concerning the effect of these strategies on left ventricular morphology and function is missing. PURPOSE The objective of our prospective randomised multicenter study in patients with persistent AF was to evaluate the effect of these two approaches on left ventricular morphology and function. METHODS The study group consisted of 205 patients (F/M 71/134; mean age 60.8 ± 11.2 years), including 101 patients randomized to the rate control approach (Group I) and 104 patients randomized to SR restoration with cardioversion and subsequent antiarrhythmic drug treatment (Group II). Mean duration of AF was 231.8 ± 112.4 days. At the end of follow-up (12 months), SR was present in 64% of patients in Group II. Echocardiographic examination was performed at a baseline and at 2 and 12 months. In the rate-control group, both right (22.1 ± 4.1 vs. 23.2 ± 3.8 cm2; p CONCLUSIONS Both strategies led to a significant increase in LV FS. Rate-control strategy led to right and left atrium enlargement, but rhythm control resulted in their decrease. |
| Databáze: | OpenAIRE |
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