Bioinformatics Analysis and Characteristics of UL14 Protein Encoded by UL14 Gene in Duck Enteritis Virus

Autor: Mingshu Wang, Anchun Cheng, Fang Jie Li
Rok vydání: 2012
Předmět:
Zdroj: Advanced Materials Research. :669-675
ISSN: 1662-8985
DOI: 10.4028/www.scientific.net/amr.424-425.669
Popis: Bioinformatics analysis was performed to predict the characteristics of the UL14 protein. The results revealing that there is no transmembrane region, and its molecular mass is 17524,9 Da, isoelectric point (IP) is 5.71. The phylogenetic tree shows that DEV-CHv is a separate branch, that is to say, DEV may be an osculant example among the herpesvirus genera. In addition the analysis of the physico-chemical properties demonstrates that UL14 has 6 main antigenic determinants and 5 phosphorylation sites. And the subcellular localization analysis indicates that UL14 is mainly located in cytoplasmic, nuclear, and mitochondrial. In conclusion, all those consequences are valuable for further researches on more accurate molecular characteristic of DEV-UL14.
Databáze: OpenAIRE