Changes in markers of bone turnover following urbanisation of black South African women

Autor: Piet J. Becker, H H Vorster, R de Winter, Marlena C. Kruger
Rok vydání: 2004
Předmět:
Zdroj: Journal of Endocrinology, Metabolism and Diabetes of South Africa. 9:8-14
ISSN: 2220-1009
1608-9677
DOI: 10.1080/22201009.2004.10872329
Popis: Objectives. To investigate dietary changes occurring with urbanisation of black South African women of different ages and how these changes influence biochemical markers of bone turnover.Design. Biochemical markers of bone turnover and resorption were determined in a subset of subjects living in the North West province of South Africa (one rural and one urban area). Women aged 15–25 years and 55–65 years were included. Food intake was measured using food frequency questionnaires. Biochemical markers were correlated with relevant changes in dietary intake that occurred with urbanisation.Results. Major findings included a significant increase in intake of animal protein, combined with very low calcium intake (< 400 mg/day). Bone turnover decreased with urbanisation as measured using osteocalcin, and bone resorption increased with urbanisation as measured with N-telopeptides from type 1 collagen (NTx), while bone formation stayed constant. These findings were prominent in the group of active growing girls (a...
Databáze: OpenAIRE