CONTRAST ENHANCED US (CEUS) 3-D IMAGES OF HYPERVASCULAR FOCAL LIVER LESIONS (FFL): FIRST RESULTS

Autor: H. P. Weskott, C. Böhm, E. von Leitner
Rok vydání: 2005
Předmět:
Zdroj: Ultraschall in der Medizin - European Journal of Ultrasound. 26
ISSN: 1438-8782
0172-4614
DOI: 10.1055/s-2005-917289
Popis: Problemstellung: Evaluation of possible diagnostic benefits of 3-D rendered Contrast Enhanced Ultrasound (CEUS) Images Methoden: CEUS (2.4mL Sonovue, Altana) was performed in 30 pts with hypervascular liver lesions (8 FNH, 6 hemangiomas, 2 HCC, 14 mets, sized 1.5cm –5cm). After conventional B-mode examination and 2-D CEUS (LOGIQ 9,GE Healthcare), CEUS 3-D volume data sets were recorded during the arterial phase (AP), portal venous (PVP) and late phase (LP) using a motor driven probe (Voluson 730 Expert, GE Healthcare). Volume acquisition started at the advent of CA and was repeated every 5 secs during the AP, twice each during the PVP and the LP. All post processing rendering parameters were set to optimize the tumor and its supplying vessels. During LP, 3-D display of signal intensities was inverted to better visualize the non-enhanced tissue. Volume calculations were performed manually and compared to volume estimation in non enhanced B-mode. FFL was characterized using the guidelines of the EFSUMB. Ergebnisse: Peri- and intratumoral vessel enhancement during AP could be imaged prior to that of liver tissue in 6/8 FNH, 8/14 Mets and 3/6 hemangiomas. Hemangiomas and FNH could clearly be delineated from liver tissue. Due to simultaneous enhancement of the adjacent or surrounding sub-segment of normal liver tissue, a sharp delineation between FLL and liver tissue could not be achieved during AP in 2/6 FNH, 3/6 hemangiomas and 6/11 mets. LA and PV branches could be differentiated by signal intensity in 22/30 pts.. During PVP and LP all mets could easily be delineated and their volume calculated. During AP the tumor volume of all mets was much bigger compared to LP calculations (22–210%). Depending on their size tumor supplying arteries could be imaged better in 5/6 FNH, 3/6 hemangiomas and all HCC than in 2/11 liver mets. Schlussfolgerungen: CEUS 3-D imaging of FFL helps to better visualize tumor blood volume during AP and number and size of supplying arteries. During LP volumes of washed out liver mets are much smaller than during AP. CEUS 3-D may help in monitoring the change of FFL volumes during treatment at different phases. Its clinical value has to be evaluated in future studies.
Databáze: OpenAIRE
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