Oat beta glucans anti-inflammatory actions in leg exercise stress
| Autor: | Jennifer Creamer Thompson, Timothy Kirby, Robert A. DiSilvestro |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0106 biological sciences
medicine.medical_specialty 030309 nutrition & dietetics medicine.drug_class Inflammation Placebo 01 natural sciences Anti-inflammatory 03 medical and health sciences 010608 biotechnology Internal medicine medicine Beta (finance) Glucan chemistry.chemical_classification 0303 health sciences Nutrition and Dietetics biology business.industry Skeletal muscle medicine.anatomical_structure Endocrinology chemistry Leg exercise Myeloperoxidase biology.protein medicine.symptom business Food Science |
| Zdroj: | Nutrition & Food Science. 51:1-9 |
| ISSN: | 0034-6659 |
| DOI: | 10.1108/nfs-01-2020-0011 |
| Popis: | Purpose Dietary fiber is not traditionally considered to have anti-inflammatory actions in skeletal muscle. This study aims to test the hypothesis that oat β-glucans fiber intake can inhibit exercise-induced inflammation. Design/methodology/approach Young adult males (age 18-30 years) consumed either oat bran β-glucans (2 × 1.5 g fiber/day) or placebo for 4 weeks (Trial 1: N = 11 for placebo, N = 9 for glucan; Trial 2: N = 7 for placebo, N = 8 for glucan). Muscle inflammatory stress was induced at baseline and post-intervention using a leg extension regimen. Findings Ingestion of β-glucans, but not placebo, protected against inflammation based on subjective soreness scores (two trials), as well as on plasma myeloperoxidase readings (one trial). Scores were subject ratings from 0 (no soreness) to 10 (injury that impairs movement). Mean soreness score was lower at 48 h after exercise stress: post-glucan treatment vs pre-treatment: Trial 1: 1.9 + 2.4 vs 3.3 + 2.2 (p = 0.05); Trial 2: 1.2 + 0.7 vs 3.9 + 2.7 (p < 0.05). Myeloperoxidase just after exercise stress increased for both groups pre-treatment, but only for the placebo group post-treatment: 62 + 12 vs 81 + 15 (p < 0.05). Originality/value This pilot study found that at least one type of dietary fiber can exert anti-inflammatory effects in skeletal muscle. |
| Databáze: | OpenAIRE |
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