Targeting cancer-associated fibroblasts with a selective PDGF-R TK inhibitor as a therapeutic approach for solid tumors

Autor:	C. Volle-Challier, M. Trombe, G. Morin, Françoise Bono, I. Blanc, M-C. Laplace, Dol, C. Labouret, G. Gueguen
Rok vydání:	2010
Předmět:	Cancer Research Pathology medicine.medical_specialty Stromal cell biology business.industry Paracrine mechanisms Therapeutic approach Oncology Tumor progression medicine biology.protein Cancer-Associated Fibroblasts business Platelet-derived growth factor receptor
Zdroj:	Journal of Clinical Oncology. 28:e13524-e13524
ISSN:	1527-7755 0732-183X
DOI:	10.1200/jco.2010.28.15_suppl.e13524
Popis:	e13524 Background: A critical step in tumor progression is the interaction of malignant and stromal cells via paracrine mechanisms. Among these stromal cells, cancer-associated fibroblasts (CAFs), ...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8739db63ea4a8828cfb8b0a9e9af8f9c https://doi.org/10.1200/jco.2010.28.15_suppl.e13524 Zobrazit plný text záznamu