Evaluation of pulmonary alveolo-capillary permeability in Type 2 diabetes mellitus
| Autor: | Mahmut Yüksel, Gözde Tuğrul, Selva Mert, Armagan Tugrul, Kemal Özşahin |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
medicine.medical_specialty
Pathology Lung medicine.diagnostic_test business.industry Endocrinology Diabetes and Metabolism Microangiopathy Type 2 Diabetes Mellitus Vascular permeability respiratory system medicine.disease Scintigraphy Gastroenterology Pulmonary function testing Endocrinology medicine.anatomical_structure DLCO Diabetes mellitus Internal medicine Internal Medicine medicine business |
| Zdroj: | Journal of Diabetes and its Complications. 20:205-209 |
| ISSN: | 1056-8727 |
| Popis: | The thickening of alveolar basement membrane is found in autopsies, along with microvascular pathologies, in Type 1 and 2 diabetes mellitus (DM). To detect the function and permeability of alveolar basement membrane, carbon monoxide diffusion capacity (DLCO) and technetium 99m-diethyltriaminepentaaceticacid ((99m)Tc-DTPA) aerosol scintigraphy methods can be used. The aim of this study was to determine alveolar basement membrane damage using these two methods. Nineteen women and 6 men, nonsmoking, Type 2 DM cases, without any lung and/or heart disease and who had neither anemia nor obesity, made up the patient group. They were compared with six female and nine male healthy cases who had the same characteristics with the diabetes cases. All of the cases DLCO were measured by single-breath method and (99m)Tc-DTPA aerosol scintigraphy was performed. DLCO showed no difference between the two groups. Aerosol scintigraphy was significantly decreased in the diabetic group (P=.01). In cases with >5 years of diabetic duration (P 8% (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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