Dexmedetomidine mitigates neuroinflammation and improves early postoperative neurocognitive dysfunction in rats by enhancing autophagy

Autor:	Jinxu Wang, Yueyang Xin, Tiantian Chu, Yaqun Zhou, Cheng Liu, Aijun Xu
Rok vydání:	2023
Předmět:	Physiology General Neuroscience
Zdroj:	Journal of Neurophysiology. 129:1145-1156
ISSN:	1522-1598 0022-3077
DOI:	10.1152/jn.00019.2023
Popis:	Dex inhibits hippocampal neuroinflammation and attenuates early cognitive impairment by enhancing autophagy following surgery in rats. Dex may protect postoperative cognitive function by activating the LKB1/AMPK/ULK-1 signaling pathway.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8724eb339ff06213789585886ff1f8ed https://doi.org/10.1152/jn.00019.2023 Zobrazit plný text záznamu