Small Cell Carcinoma of Urinary Bladder: Analysis from a Tertiary Cancer Care Center of India
| Autor: | Yogendra Singh Bhakuni, Smaranjeet Chatterjee, Himanshu Shukla, Suhas Kodasoge Rajappa, Amitabh Singh, Dharma Ram, Venkata Pradeep Babu Koyyala, Sudhir Rawal |
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| Rok vydání: | 2018 |
| Předmět: |
Limited Stage
Oncology medicine.medical_specialty Bladder cancer Urinary bladder business.industry Cancer 030209 endocrinology & metabolism Context (language use) medicine.disease Small-cell carcinoma 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure 030220 oncology & carcinogenesis Internal medicine Pediatrics Perinatology and Child Health medicine Stage (cooking) business Rare disease |
| Zdroj: | Indian Journal of Medical and Paediatric Oncology. 39:326-330 |
| ISSN: | 0975-2129 0971-5851 |
| Popis: | Context: Small cell cancer of the urinary bladder. Aims: Small cell carcinoma of the bladder is a rare histological subtype, which is particularly aggressive and global literature available describing this entity is sparse. This review of our database was to evaluate clinicopathological and survival outcomes of these patients. Subjects and Methods: The present study was a retrospective analysis of patients with small cell bladder cancer for past 6 years at Rajiv Gandhi Cancer Institute and Research Center, New Delhi. Results:: Most of the patients in our study presented with limited stage disease. The overall survival and disease-free survival (DFS) was 49% and 51.07% at 2 years, respectively. Preoperative chemotherapy with surgical resection has shown significant survival and DFS benefit. Stage at presentation also affected the survival and DFS though it did not reach statistical significance. Conclusions: Small cell bladder cancer is a rare disease with dismal prognosis. Multimodality treatment with neoadjuvant chemotherapy should be the preferred treatment for limited stage disease. |
| Databáze: | OpenAIRE |
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