Impacts of acupuncture on inflammatory cells in BALF for the asthma model rats
| Autor: | Qing Lin, Xiao-jin La, Hui-juan Liu, Ya Wang, Na Sun, Jian-mei Cui, Xiao-xi Yang |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test biology business.industry medicine.medical_treatment Intraperitoneal injection respiratory system Asthma model medicine.disease Gastroenterology respiratory tract diseases Ovalbumin Animal model Bronchoalveolar lavage Complementary and alternative medicine Internal medicine Immunology medicine Acupuncture biology.protein business Eosinophilic Granulocyte Asthma |
| Zdroj: | World Journal of Acupuncture - Moxibustion. 23:34-47 |
| ISSN: | 1003-5257 |
| DOI: | 10.1016/s1003-5257(13)60041-0 |
| Popis: | Objective To explore the impacts of acupuncture on leukocyte (LEU) and eosinophilic granulocyte (EOS) in bronchoalveolar lavage fluid (BALF) in asthma model rats. Methods Thirty SPF-grade male SD rats were randomized into a blank group, a model group and an acupuncture group, 10 rats in each one. In the acupuncture group and the model group, the intraperitoneal injection of ovalbumin (OVA) was adopted to establish asthma model. In the model group, only the animal model was established but no intervention of acupuncture was given. In the acupuncture group, at the same time of the model establishment, acupuncture was provided at Dazhuī ( GV 14), Feishū ( BL 13) and Fēngmen ( BL 12). The intervention was given once every two days, totally 7 treatments were required (2 weeks). In the blank group, no any management was applied. The lung lavage method was adopted to collect BALF after 2 weeks for the rats in each group. Under optical microscope, the total LEU count was calculated. With Wright's staining, the total EOS count was calculated. Results In the model group, LEU and EOS counts in BALF in the rats were increased apparently compared with the blank group (both P Conclusion Acupuncture intervention reduces apparently LEU and EOS counts in BALF in asthma model rats so that asthma is relieved. |
| Databáze: | OpenAIRE |
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