Autor: |
D. Veenendaal, D. van der Waaij, F. W. N. de Boer |
Rok vydání: |
1990 |
Předmět: |
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Zdroj: |
Advances in Mucosal Immunology ISBN: 9789401073233 |
DOI: |
10.1007/978-94-009-1848-1_299 |
Popis: |
In this study the colonization pattern was investigated of a mouse-related (Colonization Resistance-) microflora (CRF-MF) and an unrelated human microflora (HUM-MF) in germfree isolated C3H/Rij mice. The composition of the HUM-MF appeared to change whereas the CRF-MF did not. HUM-MF associated animals also mounted a higher serum antibody level against 50–40% of the high concentrated obligate anaerobic bacteria, whereas this fraction was less than 10% in CRF-MF mice. We conclude that the colonization of the gut is determined immunologically by the antigenic composition of the microflora for which tolerance appears to exist. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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