Eremophilane-type glucosides from the leaves of Ligularia calthifolia Maxim
| Autor: | Roman V. Doudkin, Sergey A. Dyshlovoy, Sophia D. Ermolaeva, Ludmila P. Ponomarenko, Petr G. Gorovoy |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
biology
010405 organic chemistry Chemistry Stereochemistry Plant Science Asteraceae biology.organism_classification medicine.disease 01 natural sciences Biochemistry 0104 chemical sciences 010404 medicinal & biomolecular chemistry Prostate cancer Maxim medicine Ligularia calthifolia Agronomy and Crop Science Biotechnology Prostate cells |
| Zdroj: | Phytochemistry Letters. 21:264-268 |
| ISSN: | 1874-3900 |
| DOI: | 10.1016/j.phytol.2017.07.013 |
| Popis: | Three eremophilane-type glucosides (1–3) along with three known congeners alticolosides A, B and D (4–6) have been isolated from the leaves of Ligularia calthifolia Maxim. (Asteraceae). The structures of 1–3 have been elucidated by spectroscopic analysis as well as by chemical transformations. A distinctive feature of the compounds 1–3 is the presence of an acetyl group in the glucose residues. The compounds were non-cytotoxic against human normal prostate cells as well as prostate cancer cells. |
| Databáze: | OpenAIRE |
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