Androgen receptor CAG repeat polymorphism in males of six non-human primate species
| Autor: | Robert E. Shade, Nicole Cavazos, Jeffrey Rogers, James N. Mubiru, Magdalena Garcia-Forey, Peggah Hemmat |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Genetics
congenital hereditary and neonatal diseases and abnormalities General Veterinary biology Marmoset nervous system diseases law.invention Androgen receptor chemistry.chemical_compound chemistry law biology.animal mental disorders Microsatellite Animal Science and Zoology Mangabey Repeat polymorphism Polymerase chain reaction DNA Baboon |
| Zdroj: | Journal of Medical Primatology. 41:67-70 |
| ISSN: | 0047-2565 |
| DOI: | 10.1111/j.1600-0684.2011.00517.x |
| Popis: | Background Androgen receptor [CAG]n microsatellite has been linked to human diseases. Methods Six non-human primates were genotyped for the [CAG]n microsatellite. Results Marmosets and macaques are monomorphic, while mangabeys, baboons, and chimpanzees are polymorphic. Conclusions Non-human primates that are polymorphic for the microsatellite are candidate animal models for CAG-related diseases. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text