| Autor: | David J. Callans, Francis E. Marchlinski, John J. Michele, Jian-Fang Ren, Stephen M. Dillon |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
medicine.medical_specialty
business.industry Radiofrequency ablation medicine.medical_treatment medicine.disease Ventricular tachycardia Ablation Intracardiac injection law.invention Lesion law Physiology (medical) Internal medicine Ventricular fibrillation Cardiology medicine Myocardial infarction medicine.symptom Thrombus Cardiology and Cardiovascular Medicine business Nuclear medicine |
| Zdroj: | Journal of Interventional Cardiac Electrophysiology. 5:27-32 |
| ISSN: | 1383-875X |
| DOI: | 10.1023/a:1009849622858 |
| Popis: | Introduction: The production of larger, particularly deeper lesions may improve the success rate for radiofrequency (RF) ablation of post infarction ventricular tachycardia (VT). Therapeutic RF ablation causes left ventricular (LV) mural swelling. This swelling can be detected as increased wall thickness at the ablation site by intracardiac echocardiography (ICE) and correlates with pathologic lesion size. This study compared the extent of mural swelling caused by linear ablation lesions created with irrigated tip and standard RF ablation in a porcine model of healed anterior infarction. Methods and Results: In anesthetized closed-chest swine ICE guided multiple RF applications to construct linear lesions at the border zone of the infarct region using an irrigated RF (n=6 swine) and a standard RF (n=6 swine) ablation catheter. 47 individual lesions were created with irrigated RF ablation; 57 lesions created with standard RF ablation. At all sites, wall thickness (measured at end-diastole Pre- and 1[emsp4 ]min Post-RF delivery) increased following either irrigated (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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