Solid-Phase Organic Synthesis and Combinatorial Chemistry: A Laboratory Preparation of Oligopeptides

Autor:	Karelle S. Aiken, Thomas R. Fleming, George A. Truran, J. Hodge Markgraf, Peter J. Webb
Rok vydání:	2002
Předmět:	Oligopeptide chemistry.chemical_compound Chemistry Phase (matter) Organic chemistry Leucine-enkephalin Organic synthesis General Chemistry Tripeptide Combinatorial chemistry Divergent synthesis Education
Zdroj:	Journal of Chemical Education. 79:85
ISSN:	1938-1328 0021-9584
DOI:	10.1021/ed079p85
Popis:	The principles and practice of solid-phase organic synthesis and combinatorial chemistry are utilized in a laboratory preparation of oligopeptides. A parallel synthesis scheme is used to generate a series of tripeptides. A divergent synthesis scheme is used to prepare two pentapeptides, one of which is leucine enkephalin, a neurotransmitter known to be an analgesic agent.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::86caaeb029013b65a2e360db17ff2750 https://doi.org/10.1021/ed079p85 Zobrazit plný text záznamu