Feasibility of Complete Cytoreduction in Advanced Epithelial Ovarian Cancer
| Autor: | Amal Alsonoussi, Noha E. Hassan, Mahmoud Meleis, Abdel Fattah Agameya |
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| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Open Journal of Obstetrics and Gynecology. 11:836-844 |
| ISSN: | 2160-8806 2160-8792 |
| DOI: | 10.4236/ojog.2021.117078 |
| Popis: | Objective: Complete resectability of all visualized tumor implants at debulking surgery for advanced epithelial ovarian cancer is confirmed to be the single most important prognostic factor. This study aims to develop preoperative predicting score based on clinical, biological, and radiological criteria of epithelial ovarian cancer to assess the feasibility of complete cytoreduction. Study Design: A retrospective record-based study. Patients and Methods: The study was conducted upon 50 consecutive patients managed for epithelial ovarian cancer with FIGO stage III. Patients’ data were collected from records of the Gyne-Oncology Clinic of El Shatby University Maternity Hospital affiliated to Alexandria University. Results: Many parameters were significantly associated with completeness of resectability in univariate analysis; including age, BMI, CA125, albumin, pre-albumin, PCI, mesenteric, and right copula of diaphragm affection by CT scan (p value .05). A 100-point predictability score was developed, 10 for BMI ≥ 35 kg/m2, 25 points for Pre albumin points for mesenteric affection, and 30 points for affection of Rt. copula of diaphragm. The overall accuracy of the score was 92%. Conclusion: In advanced ovarian cancer, pre-operative predicting score (including clinical, biological, and radiological criteria) can be used as a roadmap for prediction of feasibility of complete resectability. However, more research is needed on larger sample sizes. |
| Databáze: | OpenAIRE |
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