Oncogenic Kinases in Cancer
Autor: | Alexandros Zafiropoulos, Antonis Tsintarakis |
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Rok vydání: | 2017 |
Předmět: | |
Zdroj: | eLS |
DOI: | 10.1002/9780470015902.a0006051.pub3 |
Popis: | Oncogenesis involves the generation and transmission of signals that result in deregulation of cell proliferation, inhibition of apoptosis and morphological changes. Transmembrane or cytoplasmic tyrosine and serine/threonine kinases participate both directly and indirectly in cell transformation and tumorigenesis. Keywords: tyrosine kinases; receptor kinases; serine/threonine kinases; cell cycle; apoptosis |
Databáze: | OpenAIRE |
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