Oncogenic Kinases in Cancer

Autor: Alexandros Zafiropoulos, Antonis Tsintarakis
Rok vydání: 2017
Předmět:
Zdroj: eLS
DOI: 10.1002/9780470015902.a0006051.pub3
Popis: Oncogenesis involves the generation and transmission of signals that result in deregulation of cell proliferation, inhibition of apoptosis and morphological changes. Transmembrane or cytoplasmic tyrosine and serine/threonine kinases participate both directly and indirectly in cell transformation and tumorigenesis. Keywords: tyrosine kinases; receptor kinases; serine/threonine kinases; cell cycle; apoptosis
Databáze: OpenAIRE