Fibrous dysplasia of the bone. Contribution of Nuclear Medicine in the Diagnosis of Suspicion of Sarcomatous Degeneration
| Autor: | M. Tello Moreno, C. Ramos Font, A.C. Rebollo Aguirre, M. Navarro-Pelayo Láinez, M. Gallego Peinado, J.M. Llamas Elvira, A. Santiago Chinchilla |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Microbiology (medical)
medicine.medical_specialty Pathology Bone disease business.industry Fibrous dysplasia Immunology Mesenchyma Context (language use) Degeneration (medical) medicine.disease Malignancy Malignant transformation medicine Immunology and Allergy Radiology Differential diagnosis Nuclear medicine business |
| Zdroj: | Revista Española de Medicina Nuclear (English Edition). 29:172-176 |
| ISSN: | 1578-200X |
| DOI: | 10.1016/s1578-200x(10)70049-8 |
| Popis: | Fibrous dysplasia is a relative frequent benign bone disease in which there is a maturation disorder of the bone-forming mesenchyma where the lamellar bone marrow is replaced with abnormal fibrous tissue. Its diagnosis is often an accidental finding when X-ray studies or bone scans are performed for other reasons since it is usually asymptomatic. There may be complications such as deformities, pathological fractures and exceptionally malignant transformation. The differential diagnosis between malignancy and FD can be complicated and lead to late diagnosis when sarcomatous degeneration already exists. In this context, 18 F-fluorodeoxyglucose positron emission tomography (FDG-PET) may be useful in the monitoring of this condition. We present two cases of patients diagnosed with FD with suspicion of malignization of their bone lesions who were referred for complementary imaging studies of Nuclear Medicine. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|