Flow behaviour in normal and Meniere’s disease of endolymphatic fluid inside the inner ear
| Autor: | Muhammad Sufyan Amir Paisal, Normayati Nordin, Suzairin Md Seri, Nofrizalidris Darlis, Yahaya Ramli, Kahar Osman, Ahmad Zahran Md Khudzari, Muhamad Azmi Wahab, Ishkrizat Taib, Norasikin Mat Isa |
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| Rok vydání: | 2017 |
| Předmět: |
Pressure drop
medicine.medical_specialty Materials science Ductus reuniens 0206 medical engineering Cochlear duct 02 engineering and technology Anatomy Audiology medicine.disease 020601 biomedical engineering Endolymphatic sac Endolymphatic duct 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure medicine Vestibular membrane Inner ear 030223 otorhinolaryngology Meniere's disease |
| Zdroj: | IOP Conference Series: Materials Science and Engineering. 243:012033 |
| ISSN: | 1757-899X 1757-8981 |
| DOI: | 10.1088/1757-899x/243/1/012033 |
| Popis: | Meniere's disease is a rare disorder that affects the inner ear which might be more severe if not treated. This is due to fluctuating pressure of the fluid in the endolymphatic sac and dysfunction of cochlea which causing the stretching of vestibular membrane. However, the pattern of the flow recirculation in endolymphatic region is still not fully understood. Thus, this study aims to investigate the correlation between the increasing volume of endolymphatic fluid and flow characteristics such as velocity, pressure and wall shear stress. Three dimensional model of simplified endolymphatic region is modeled using computer aided design (CAD) software and simulated using computational fluid dynamic (CFD) software. There are three different models are investigated; normal (N) model, Meniere's disease model with less severity (M1) and Meniere's disease model with high severity (M2). From the observed, the pressure drop between inlet and outlet of inner ear becomes decreases as the outlet pressure along with endolymphatic volume increases. However, constant flow rate imposed at the inlet of endolymphatic showing the lowest velocity. Flow recirculation near to endolymphatic region is occurred as the volume in endolympathic increases. Overall, high velocity is monitored near to cochlear duct, ductus reuniens and endolymphatic duct. Hence, these areas show high distributions of wall shear stress (WSS) that indicating a high probability of endolymphatic wall membrane dilation. Thus, more severe conditions of Meniere's disease, more complex of flow characteristic is occurred. This phenomenon presenting high probability of rupture is predicted at the certain area in the anatomy of vestibular system. |
| Databáze: | OpenAIRE |
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