Diastereoselective Specificity for the Hydrolysis of Dipeptide Esters in Aqueous Media

Autor:	Kouichi Goto, Yukito Murakami, Ryuichi Ueoka, Chikara Imamura, Shinya Yoshimitsu, Yasuji Ihara, Atsushi Miki, Osamu Tanoue
Rok vydání:	1999
Předmět:	Hydrolysis chemistry.chemical_compound Aqueous solution Dipeptide Reaction temperature Aqueous medium Chemistry Organic chemistry General Chemistry
Zdroj:	Chemistry Letters. 28:73-74
ISSN:	1348-0715 0366-7022
DOI:	10.1246/cl.1999.73
Popis:	The diastereoselectivity for the hydrolysis of p-methoxycarbonylphenyl N-(benzyloxycarbonyl)-D(L)-phenylalanyl-L-leucinate in aqueous solution was inverted by changing concentrations of the substrates or the reaction temperature. The monomer-aggregate transition operated on the LL-substrate, which was suggested by the spectroscopic measurements, seems to be responsible for such behavior.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8686138a522b73ceea8b7b7c48e37a58 https://doi.org/10.1246/cl.1999.73 Zobrazit plný text záznamu