X-ray scattering study of the interactions between magnetic nanoparticles and living cell membranes
| Autor: | Darryl N. Williams, Isaac Koh, L. J. Martínez-Miranda, Tracey R. Pulliam Holoman, Sheryl H. Ehrman, Bani H. Cipriano |
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| Rok vydání: | 2005 |
| Předmět: | |
| Zdroj: | Journal of Applied Physics. 97:084310 |
| ISSN: | 1089-7550 0021-8979 |
| Popis: | Magnetic nanoparticles (MNPs) have found increased applicability in drug delivery, cancer treatment, and immunoassays. There is a need for an improved understanding of how MNPs interact with living cell membranes in applied magnetic fields to use them effectively. The interactions between Escherichia coli (E. coli) and SiO2∕γ-Fe2O3 composite particles in magnetic fields were studied using x-ray scattering. Magnetic field strengths up to 423mT were applied to the samples to see the effects of the magnetic fields on the E. coli membranes in the presence of the magnetic particles in the cell cultures. X-ray scattering results from continuous cultures of E. coli showed two peaks, a sharp peak at q=0.528A−1 (1.189nm) up to 362mT of magnetic field strength and a diffuse one at q=0.612A−1 (1.027nm). The sharp peak was shifted to the smaller side of q when magnetic particles were added and the magnitude of the applied magnetic field strength was increased from 227to298mT, to 362mT, whereas the diffuse peak did no... |
| Databáze: | OpenAIRE |
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