Fluence Compensation for Improving Quantitative Photoacoustic Spectroscopy
| Autor: | Alexander Pattyn, Mohammad Mehrmohammadi, Naser Alijabbari |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Materials science
business.industry 0206 medical engineering Ultrasound 02 engineering and technology Iterative reconstruction 020601 biomedical engineering 01 natural sciences Fluence Imaging phantom Compensation (engineering) 010309 optics Optics Amplitude Homogeneous 0103 physical sciences business Photoacoustic spectroscopy |
| Zdroj: | 2020 IEEE International Ultrasonics Symposium (IUS). |
| DOI: | 10.1109/ius46767.2020.9251530 |
| Popis: | Photoacoustic tomography (PAT) is a non-invasive, high-resolution imaging modality capable of providing functional and molecular information about various pathologies, such as cancer. In PAT imaging, the depth dependent light attenuation limits the fluence as a function of depth and thereby reduces the PA amplitude of signals from deeper regions of tissue. This makes it impossible to equally compare signals from various depths and causes inaccuracies when measuring spectroscopic-based measurands such as oxygen saturation levels. Previous fluence compensations studies used a homogeneous assumption for optical properties of the phantom or compensated relatively small objects. In this work, we propose an algorithm in which PAT images are compensated for the speed-of-sound (SOS) and optical heterogeneities. Keywords—Photoacoustics, ultrasound, fluence compensation, image reconstruction. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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