Synthesis of pyrrolo[1,2-a][1,6]benzodiazonines from pyrrolo[1,2-a][1,4]benzodiazepines and alkynes containing electron-acceptor substituents

Autor:	M. I. Babakhanova, Tatiana N. Borisova, Leonid G. Voskressensky, T. M. Chervyakova, A. V. Butin, T. A. Nevolina, Victor N. Khrustalev, Alexey V. Varlamov, Alexander A. Titov
Rok vydání:	2013
Předmět:	chemistry.chemical_classification chemistry.chemical_compound Diazepine chemistry Organic Chemistry Electron acceptor Cleavage (embryo) Ring (chemistry) Formyl group Medicinal chemistry Pyrrole
Zdroj:	Chemistry of Heterocyclic Compounds. 49:1024-1032
ISSN:	1573-8353 0009-3122
Popis:	It has been established that the reaction of pyrrolo[1,2-a][1,4]benzodiazepines with activated alkynes gives pyrrolo[1,2-a][1,6]benzodiazonines as the products of diazepine ring expansion. In the case of pyrrolo[1,2-a][1,4]benzodiazepine, substituted with formyl group at the pyrrole ring, both expansion and cleavage of the diazepine fragment can occur.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::864c54016361b87e110311badc73a7bb https://doi.org/10.1007/s10593-013-1340-z Zobrazit plný text záznamu Plný text ve formátu PDF