Vesiculo-Bullous Eruption Following COVID Vaccination
| Autor: | Raghda Saeed Al Maashari, Al Mahmood Noaf S, Saleem Tausif |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Saudi Journal of Medicine. 7:501-504 |
| ISSN: | 2518-3397 2518-3389 |
| DOI: | 10.36348/sjm.2022.v07i09.007 |
| Popis: | Bullous pemphigoid (BP) is an autoimmune sub-epidermal bullous disorder with a complex etiopathogenesis, predominately affecting the elderly. We report a case of COVID vaccination- induced BP, in a 30-year-old previously healthy Indian male who presented with a 1month history of itchy generalized vesiculo-bullous eruption that developed 3 days after receiving the first dose of the COVID vaccination. Histological examination and direct immunofluorescence study showed a sub-epidermal blister with a dermal inflammatory infiltrate and linear epidermal staining of IgG and C3 along the basement membrane zone in an n-serrated pattern. Treatment with oral prednisolone and oral doxycycline resulted in significant improvement in his condition. To our knowledge, there are limited case reports to date particularly in the Middle-East, which describe BP triggered by COVID vaccination. |
| Databáze: | OpenAIRE |
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