Liquid-phase photofluorination with elemental fluorine. Part II. Synthesis of perfluorotertiary amines
| Autor: | Kouichi Yamanouchi, Kirby V. Scherer, Taizo Ono |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Organic Chemistry
chemistry.chemical_element Regioselectivity Liquid phase Biochemistry Medicinal chemistry Electrochemical fluorination Adduct Inorganic Chemistry Metal chemistry.chemical_compound chemistry Pentene visual_art Fluorine visual_art.visual_art_medium Environmental Chemistry Organic chemistry Amine gas treating Physical and Theoretical Chemistry |
| Zdroj: | Journal of Fluorine Chemistry. 73:267-272 |
| ISSN: | 0022-1139 |
| Popis: | The tertiary amines derived from hexafluoropropene dimers were subjected to liquid-phase photofluorination (LPPF). The corresponding perfluorotertiary amines, which were difficult to synthesize by the conventional fluorination methods such as electrochemical fluorination and indirect fluorination using high-valency metal fluorides, were obtained in good yields. Prepared by this method were F -( N,N -dimethyl-2- methylpentyl) amine 3 , F -( N,N -diethyl-2-methylpentyl) amine 4 , F -3-(1-pyrrolidino)-2-methylpentane 11 , F - ( N,N -dimethyl-1,1-dimethyl-butyl) amine 13 . Discussion on the regioselectivity in the reaction of F -2-methyl-2-pentene (D-II) with secondary amines is also included in connection with the necessity of preparing a regioselective adduct,3-(1-pyrrolidino)- F -2-methyl-2- pentene, for the synthesis of 11 . |
| Databáze: | OpenAIRE |
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