ChemInform Abstract: Casein Kinase II Inhibitors Isolated from Two Brazilian Plants Hymenaea parvifolia and Wulffia baccata

Autor:	Sérgio de Mello Alves, Kiichiro Kawaguchi, Masami Ishibashi, Emi Okuyama, Kenzo Ohtsuki, Toshiro Maekawa, Takashi Watanabe, Kanki Komiyama, Mana Mitamura, Hiroko Oda
Rok vydání:	2010
Předmět:	Terpene Hymenaea parvifolia Biochemistry Eukaryotic Large Ribosomal Subunit Chemistry visual_art visual_art.visual_art_medium Bark Pentacyclic triterpenoids General Medicine Casein kinase 2 Ribosomal P In vitro
Zdroj:	ChemInform. 30
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.199946217
Popis:	Two dihydroflavonol rhamnosides (1 and 2) isolated from the bark of Hymenaea parvifolia and two pentacyclic triterpenoids (3 and 6) obtained from the leaves of Wulffia baccata have been found to exhibit inhibitory effects of casein kinase II (CK-II) dose-dependently, suggesting that at higher doses more than 10 μM, these four compounds may act as potent CK-II suppressors of the CK-II mediated activation of 60S acidic ribosomal P proteins in vitro.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::863d16ba3aaa70d0d65b592cd17a9959 https://doi.org/10.1002/chin.199946217 Zobrazit plný text záznamu Plný text