| Autor: |
Jean W. Lee, Jin Wang, Yuling Wu |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Biomarkers in Drug Discovery and Development. :149-176 |
| Popis: |
The use of novel biomarkers has become a prominent component of decision-making processes in drug development. They are used in the in vitro and preclinical models and early clinical phase for quick-hit and early-attrition decisions. This article focuses on quantitative method validation and assay for biomarker characterization to support drug development using the fit-for-purpose approach. Keywords: biomarkers; in vitro models; fit-for-purpose approach; protein expression |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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