Exposure to environmental tobacco smoke and risk of adenocarcinoma of the lung
Autor: | Lorenzo Simonato, Valerie Gaborieau, Wolfgang Ahrens, Halina Batura-Gabryel, Cristina Fortes, Simone Benhamou, Irene Brüske-Hohlfeld, Anush Mukeria, Fredrik Nyberg, Vali Constantinescu, Paolo Boffetta, Suzanne Lea |
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Rok vydání: | 1999 |
Předmět: |
Cancer Research
medicine.medical_specialty education.field_of_study Passive smoking business.industry Population Case-control study Odds ratio medicine.disease_cause medicine.disease Tobacco smoke Surgery Oncology Environmental health Epidemiology medicine Adenocarcinoma of the lung Risk factor education business |
Zdroj: | International Journal of Cancer. 83:635-639 |
ISSN: | 1097-0215 0020-7136 |
Popis: | We conducted a case-control study of adenocarcinoma of the lung and exposure to environmental tobacco smoke (ETS) in 7 countries. We interviewed 70 cases of adenocarcinoma of the lung and 178 population or hospital controls. All subjects had smoked fewer than 400 cigarettes in their lifetimes. Ever exposure to ETS from the parents during childhood was associated with a decreased risk [odds ratio (OR) 0.6, 95% confidence interval (CI) 0.3-1.2], and there was a suggestion of a decreasing trend in risk with increasing duration of exposure. Ever exposure to ETS from the spouse was not associated with an increased risk (OR 1.0, 95% CI 0.5-1.8), while the OR of ever exposure to ETS at the workplace was 1.5 (95% CI 0.8-3.0). For both exposure sources, an increased risk was observed among the highly exposed, and the OR among those with the highest duration of exposure to ETS from the spouse or at the workplace was 1.8 (95% CI 0.5-6.2). A similar risk was estimated for current exposure to ETS from either source. Our results confirm previous reports of a weak effect of adult ETS exposure on risk of adenocarcinoma of the lung. Bias and confounding cannot be excluded as explanations for the apparent decrease in risk from childhood exposure. |
Databáze: | OpenAIRE |
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