Antibacterial Effect of Thiosulfinates on Multiresistant Strains of Bacteria Isolated from Patients with Cystic Fibrosis
| Autor: | Tatyana V. Demidkina, Vasily Koval, Elena A. Morozova, D G Kuliastova, L.R. Avetisyan, A N Rodionov, S.V. Revtovich, I.A. Shaginyan, Vitalia V. Kulikova, M.Yu. Chernukha |
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| Rok vydání: | 2018 |
| Předmět: |
Allicin
biology Microorganism Antibacterial effect biology.organism_classification medicine.disease Biochemistry Cystic fibrosis Microbiology chemistry.chemical_compound chemistry medicine Molecular Medicine Antibacterial activity Molecular Biology Thiosulfinate Antibiotic Drugs Bacteria Biotechnology |
| Zdroj: | Acta Naturae. 10:77-80 |
| ISSN: | 2075-8251 |
| DOI: | 10.32607/20758251-2018-10-3-77-80 |
| Popis: | The multiresistance of A. ruhlandii 155B, B. cenocepacia 122, and P. aeruginosa 48B strains isolated from patients with cystic fibrosis was established. The antibacterial effect of allicin, dimethyl thiosulfinate, and dipropyl thiosulfinate on multidrug-resistant strains was shown. Thiosulfinates can have both bacteriostatic and bactericidal effects depending on the microorganism and the concentration. The studied thiosulfinates may be candidates for the development of alternative antibiotic drugs to treat infections caused by multidrug-resistant pathogens. |
| Databáze: | OpenAIRE |
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