S4–04–02: M1 muscarinic agonists as a comprehensive therapy in Alzheimer's disease
| Autor: | Antonela Caccamo, Abraham Fisher, Kim N. Green, Rachel Brandeis, Hanoch Elkon, Z. Pittel, Lauren M. Billings, Salvatore Oddo, Nira Bar-Ner, Frank M. LaFerla |
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| Rok vydání: | 2006 |
| Předmět: |
medicine.medical_specialty
Epidemiology business.industry Health Policy Disease Psychiatry and Mental health Cellular and Molecular Neuroscience Developmental Neuroscience medicine Reversing Disease process Neurology (clinical) Geriatrics and Gerontology Intensive care medicine business Contextual memory |
| Zdroj: | Alzheimer's & Dementia. 2 |
| ISSN: | 1552-5279 1552-5260 |
| DOI: | 10.1016/j.jalz.2006.05.285 |
| Popis: | contextual memory was also measured. Conclusions: We have identified a number of development candidates aimed at targeting either improved symptomatic therapy or disease slowing. This ‘multiple shots on goal’ approach using multiple platforms and multiple targets will help to increase the likelihood of delivering novel therapeutics to patients. Ultimately, the success of our programs, will be judged by our ability to deliver novel therapies to patients with significant positive impact on their lives, and a slowing, halting or perhaps even reversing of this devastating disease process. |
| Databáze: | OpenAIRE |
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