Selective Action of Gentian Violet on Enzymes

Autor: Alvin Y. Wells, Noble P. Sherwood
Rok vydání: 1934
Předmět:
Zdroj: Journal of Infectious Diseases. 55:356-359
ISSN: 1537-6613
0022-1899
DOI: 10.1093/infdis/55.3.356
Popis: In previous publications we 1 have shown the existence of a selective action of gentian violet and crystal violet on bacteriophages. The results obtained also present evidence that there is a correlation between the selective action of the dyes on bacteria and on their respective phages. Because several investigators have suggested the enzyme-like nature of the bacteriophage and because the two biologic substances present many similar properties a study of the effect of dye on enzymes seemed to be a logical investigation to follow the aforementioned work on the action of dye on bacteriophages. The chief objective in the experimental work reported in this study was to see whether a similarity exists between the action of dye on bacterial enzymes and its action on the corresponding bacteria, as was found with the bacteriophages. The following observations were also noted: the effect of various reactions of mediums on enzyme activity and the quantity and speed of liquefaction of gelatin by the different
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