Increased C-reactive protein and fever in Japanese infants with food protein-induced enterocolitis syndrome
| Autor: | Hideaki Morishita, Fumika Tokunaga, Yasunori Ito, Mitsuaki Kimura, Takaaki Meguro, Shiro Seto, Masaki Shimomura |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Enterocolitis
medicine.medical_specialty Pediatrics Disease onset Oral food challenge business.industry Increased C-reactive protein medicine.disease Gastroenterology Food protein-induced enterocolitis syndrome 03 medical and health sciences 0302 clinical medicine 030228 respiratory system 030225 pediatrics Internal medicine Pediatrics Perinatology and Child Health medicine Ingestion medicine.symptom business |
| Zdroj: | Pediatrics International. 58:826-830 |
| ISSN: | 1328-8067 |
| DOI: | 10.1111/ped.12938 |
| Popis: | Background Increased C-reactive protein (CRP) and fever are observed in some infants with food protein-induced enterocolitis syndrome (FPIES) in Japan, but the reproducibility of these findings has not yet been confirmed on oral food challenge (OFC). Methods Fourteen infants with FPIES induced by cow's milk (CM) formula were enrolled. OFC using CM formula was performed on each infant once or repeatedly (total 18 tests), with a stepwise incremental protocol in an infection-controlled setting. CRP was measured 24 h after the last ingestion of the CM formula. Results Increased CRP was observed in 11 of the 18 OFC conducted (median, 2.60 mg/dL; range, 0.22–4.84 mg/dL). Fever was induced in six occasions during OFC. Serum CRP in the patients with fever increased to median 3.76 mg/dL (range |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text