A reanalysis of the evidence for increased efficiency in benzene metabolism at airborne exposure levels below 3 p.p.m

Autor: Donald D. Fontaine, Tim D. Rey, Paul S. Price, Scott M. Arnold
Rok vydání: 2012
Předmět:
Zdroj: Carcinogenesis. 33:2094-2099
ISSN: 1460-2180
0143-3334
DOI: 10.1093/carcin/bgs257
Popis: An analysis of monitoring data on workers in Tianjin, China, reported a 9-fold increase in the production of benzene metabolites per unit exposure as air concentrations declined from 88.9 to 0.03 p.p.m. The increase is attributed to an enhanced efficiency of benzene metabolism at lower air concentrations. This finding, however, is not consistent with other studies demonstrating that adsorbed benzene is almost completely metabolized at airborne levels ranging from
Databáze: OpenAIRE