ChemInform Abstract: Reactions of Nitrilium Salts with Indole and Pyrrole and Their Derivatives in the Synthesis of Imines, Ketones and Secondary Amines

Autor:	Harry Heaney, Giles Robert Gordon, M. John Plater
Rok vydání:	2016
Předmět:	Indole test Hydrolysis chemistry.chemical_compound Sodium borohydride Aqueous solution chemistry Imine Organic chemistry General Medicine Methanol Nitrilium Pyrrole
Zdroj:	ChemInform. 47
ISSN:	0931-7597
DOI:	10.1002/chin.201601119
Popis:	Reactions of N-methyl- and N-ethyl-nitrilium salts with indole and pyrrole and their derivatives yield imines or imine salts in good yields. The related imines are obtained from the salts after careful basification and hydrolysis of the imine salts or the imines by heating with aqueous base give the related ketones in good yields. Alternatively, the imine salts can be reduced using sodium borohydride in methanol to give the related secondary amines.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::85d60adc511b8781181fec173854c1e5 https://doi.org/10.1002/chin.201601119 Zobrazit plný text záznamu Plný text