Subjective Sleep Quality as it Relates to Cognitive and Physical Function in Spinal Muscular Atrophy Patients

Autor: Alexandra Wennberg, Sabrina Lenzoni, Pierpaolo Turcano, Elena Casagrande, Luca Caumo, Gianni Sorarú, Elena Pegoraro, Carlo Semenza
Rok vydání: 2023
Předmět:
Zdroj: Journal of Neuromuscular Diseases. :1-5
ISSN: 2214-3602
2214-3599
DOI: 10.3233/jnd-221627
Popis: Sleep quality and its association with cognition has been widely studied in some neurodegenerative diseases, but less is known about this association in spinal muscular atrophy (SMA). In adult SMA (n = 21) patients and age-matched controls (n = 23), we assessed subjectively measured sleep quality and daytime somnolence. Cognition was assessed with a multi-domain neuropsychological battery. Further, we investigated the association between clinical functional scores and sleep questionnaire scores. Among SMA patients, better motor and limb function was associated with better subjective sleep quality (p’s< 0.05). Clinicians should consider sleep quality in patient care and future studies are needed to better understand these relationships.
Databáze: OpenAIRE